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尿激酶抑制劑篩選試劑盒

Urokinase Inhibitor Screening Kit
產(chǎn)品編號:3258126
產(chǎn)品類別:試劑盒
純度規(guī)格:Sufficient for 100 Fluorometric tests
包裝規(guī)格:1 KIT
市場價:6880元
優(yōu)惠價:立即咨詢

尿激酶抑制劑篩選試劑盒

Urokinase Inhibitor Screening Kit

uPA Inhibitor Screening Kit

Urokinase-type Plasminogen Activator Inhibitor Screening Kit

Plasminogen Activator Inhibitor Screening Kit

纖溶酶原激活劑抑制劑篩選試劑盒

uPA抑制劑篩選試劑盒

激酶型纖溶酶原激活劑抑制劑篩選試劑盒

基本信息
NACRES
NA.25
General description【一般描述】
Urokinase (Urokinase-type plasminogen activator, uPA, EC 3.4.21.73) is a serine protease involved in the degradation of extracellular matrix components. It cleaves the Arg-Val bond in plasminogen and converts it to plasmin. The activity of uPA is important in tumor cell proliferation and migration. Polymorphisms in uPA gene are reportedly associated with Alzheimer′s disease.
Principle【原理】
The Urokinase Inhibitor Screening Kit is a rapid, simple and sensitive assay that is suitable for the screening of Urokinase inhibitors. Urokinase activity is measured by cleaving a synthetic 7-amino-4-trifluoromethylcoumarin (AFC)-based substrate to yield AFC, a fluorescent product (λex = 350/ λem = 450 nm), proportional to the enzymatic activity present.
Components【組分】
組份不可單獨銷售
Urokinase Assay Buffer
Urokinase Substrate
Human Urokinase
Urokinase Inhibitor; 10 mM GGACK Dihydrochloride
產(chǎn)品性質(zhì)
Detection Method
fluorometric
storage temp.【儲存溫度】
−20℃
Gene Information
human ... PLAU(5328)
mouse ... PLAU(18792)
rat ... PLAU(25619)
suitability【適用性】
適于篩選尿激酶抑制劑。
安全信息
Pictograms【象形圖】
GHS08
Signal word【警示用語:】
Danger
Hazard Statements
H334
Precautionary Statements
P261 - P284 - P501
Hazard Classifications【危險分類】
Resp. Sens. 1
Storage Class Code【儲存分類代碼】
10 - Combustible liquids
WGK
WGK 3
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